Guides Collective
The Weekly Guide
Resources, research, and reflections — curated each week for the guides in our community.
MAY 29, 2026
Section 01
Industry Headlines
What's happening in the psychedelic space this week.
MEDICALXPRESS · MAY 5, 2026
One Dose of Psilocybin Changes the Human Brain, Leading to Higher Entropy
A landmark study from UCSF and Imperial College London found that a single dose of psilocybin produces measurable changes in brain connectivity — increasing neural entropy in ways associated with lasting improvements in mood and cognition.
COMPASS PATHWAYS · FEBRUARY 17, 2026
Psilocybin Passes Second Phase 3 Trial — Compass Pathways Eyes FDA Filing in Q4 2026
Compass Pathways announced that COMP360 psilocybin met its primary endpoint in a second Phase 3 trial for treatment-resistant depression — with 39% of participants in the 25 mg arm showing clinically meaningful symptom reduction and rapid onset beginning the day after a single dose. The company plans to file a New Drug Application with the FDA in Q4 2026, potentially making psilocybin the first approved psychedelic treatment for depression.
MEDICALXPRESS · MAY 4, 2026
Cannabis Leads US Microdosing, With 24.1 Million Adults Reporting Lifetime Use
A University of California San Diego study found that 24.1 million American adults have tried microdosing cannabis — with growing use among those seeking mental health benefits and performance enhancement.
Section 02
From the Field
Perspectives and insights from leaders in the psychedelic space.
A.C. Redick · Lucid News
Learning to Die Well: Inside a Psychedelic End-of-Life Retreat
Reverend Bodhi Be's vision for transforming end-of-life care materialized through the inaugural retreat of the Ram Dass Institute of Psychedelic Studies with the Dying — bringing seventy practitioners to Maui to explore how psychedelics can support conscious dying.
Jack Gorsline · Lucid News
Evaluating the Pros and Cons of State Psychedelic Task Forces
States are increasingly establishing task forces to study psychedelic-assisted therapies — with some jurisdictions seeing recommendations translate into action while others face criticism for using commissions to delay rather than accelerate meaningful reform.
Section 03
Personal Journeys
First-person accounts worth reading — perspectives that inform the work we do.
LUCID NEWS · MAY 13, 2026
Football Player Jordan Poyer Leads the Breath of Life Tour
Former NFL safety Jordan Poyer documents his journey organizing the Breath of Life Tour — bringing breathwork and somatic healing practices to communities across the country in the wake of his own transformative recovery experience.
NORMALIZE PSYCHEDELICS · MAY 7, 2026
The Spider Speaks: Healing From Childhood Sexual Abuse Through Plant Medicine and the Ring
A survivor of childhood sexual abuse shares how a combination of plant medicine ceremonies and combat sports became an unexpected path toward integration, reclaiming the body, and finding a language for trauma that years of conventional therapy could not reach.
Section 04
From the Platform
What's new and coming to Guides Collective.
Looking into better analytics tools to assess seeker behavior on the platform
Until then we're pausing all UX updates until we have a better understanding of user drop offs